Cellular biophysics and modeling : a primer on the computational biology of excitable cells / Greg Conradi Smith.

By: Smith, Greg Conradi [author]Material type: TextTextPublisher: Cambridge ; New York, NY : Cambridge University Press, c2019Description: xii, 382 pages ; 25 cm. illustrationsISBN: 978-0-521-18305-5Subject(s): EXCIATATION (PHYSIOLOGY) -- MATHEMATICAL MODELS | BIOPHYSISCS | CELL PHYSIOLOGY | COMPUTATIONAL BIOLOGYLOC classification: QP 363 S65 2019
Contents:
Compartmental modeling -- Phase diagrams -- Ligands, receptors & rate laws -- Function families & characteristic times -- Bifurcation diagrams of scalar ODEs -- The Nernst equilibrium potential -- The current balance equation -- GHK theory of membrane permeation -- Voltage-gated ionic currents -- Regenerative ionic currents and bistability -- Voltage-clamp recording -- Hodgkin-Huxley model of the action potential -- The Morris-Lecar model -- Phase plane analysis -- Linear stability analysis -- Type II excitability and oscillations (the Hopf bifurcation) -- Type I excitability and oscillations (SNIC & SHO bifurcations) -- The low-threshold calcium spike -- Synaptic currents.
Summary: "It must also be supposed that the cell bodies and the dendrites are, in the same way as the axis cylinders, conductive devices, as they represent the intermediary links between afferent nerve fibres and the afore-mentioned axons"-- Provided by publisher.
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NU Fairview College LRC
School of Arts and Sciences General Circulation GC QP 363 S65 2019 (Browse shelf(Opens below)) Available NUFAI000004820

Includes index.

Compartmental modeling -- Phase diagrams -- Ligands, receptors & rate laws -- Function families & characteristic times -- Bifurcation diagrams of scalar ODEs -- The Nernst equilibrium potential -- The current balance equation -- GHK theory of membrane permeation -- Voltage-gated ionic currents -- Regenerative ionic currents and bistability -- Voltage-clamp recording -- Hodgkin-Huxley model of the action potential -- The Morris-Lecar model -- Phase plane analysis -- Linear stability analysis -- Type II excitability and oscillations (the Hopf bifurcation) -- Type I excitability and oscillations (SNIC & SHO bifurcations) -- The low-threshold calcium spike -- Synaptic currents.

"It must also be supposed that the cell bodies and the dendrites are, in the same way as the axis cylinders, conductive devices, as they represent the intermediary links between afferent nerve fibres and the afore-mentioned axons"-- Provided by publisher.

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